![]() Older patients with B-cell malignancies were at increased risk for death (unlike older patients with metastatic solid tumors), as were all patients with cancer who smoke tobacco. The 90-day mortality rate for pre-June patients was 28% (21% to 34%) compared with 21% (13% to 28% P =. Patients diagnosed with SARS-CoV-2 before June 2020 had 30-day mortality rate of 20% (95% CI, 14% to 25%) compared with 13% (8% to 18%) for those diagnosed in or after June 2020 ( P =. Tobacco users had 30-day mortality estimate of 21% compared with 11% for never users (log-rank P =. Association between survival and age was not significant in patients with metastatic solid tumors ( P =. Patients with B-cell malignancies age 61-70 years had twice mortality risk (hazard ratio = 2.1 ) and those age > 70 years had 4.5 times mortality risk (95% CI, 1.8 to 11.1) compared with patients age ≤ 60 years. Forty-three percent were current or previous cigarette users. Sixty-two percent had regional or metastatic solid tumors. Thirty-eight practices provided data for 453 patients from April to October 2020. Primary outcomes are 30- and 90-day mortality rates and change over time. ![]() ![]() In this analysis, we focus on all patients with hematologic or regional or metastatic solid tumor malignancies. Participating practices enter data on patients with SARS-CoV-2 infection in cancer treatment. ASCO's COVID-19 registry promotes systematic data collection across US oncology practices. People with cancer are at increased risk for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. ![]()
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